4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" data-v-3f5bad52="" class="" style="">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="navbar1-div">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="row clearfix">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="col-md-12">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_window" style="display: none;">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_Model">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>9 search-wind-close" style="color: rgb(0, 0, 04 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;">
4
-14>="" class="search-product-content">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4
-14>="" class="iconfont icon-zu4
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4
-14>="" class="search_bearfruit Jso-M-Title" data-top="layerCB84
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4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_btn_nav_content">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_btn_content">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_product_btn">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;"> 4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;">
4
-14>="" class="search_product_input" style="border: 1px solid rgb(213, 213, 2134
-24
-14>="" class="searchicon-product-icon iconfont icon-zu2703 right10" style="color: rgb(213, 213, 2134
-24
-14>="" type="text" placeholder="请输入关键字" style="color: rgb(0, 0, 04
-24 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>631F3D098DC3E3F3859862ECB31B" data-expr="attr.options.btntxt" data-index="-1" data-ckey="jso_Btn" style="border: 0px solid rgb(255, 255, 2554 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>; border-top-left-radius: 0px; border-top-right-radius: 0px; border-bottom-right-radius: 0px; border-bottom-left-radius: 0px; color: rgb(255, 255, 2554 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;">搜索
4
-14>="" nocolor="true" class="search_btn Jso-Btn Jso-Assistance-Col1" data-top="layerCB84
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4
-14>="" class="search_bearfruit_tab">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>; --active-sline-color: #000;">
4
-14>="" class="search_tab_cont" style="border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(213, 213, 2134
-24 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>631F3D098DC3E3F3859862ECB31B" data-expr="attr.options.searchTabArtLeft" data-index="-1" data-ckey="searchTabArtLeftFont">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>-0 4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>631F3D098DC3E3F3859862ECB31B" data-expr="attr.options.searchTabArtRight" data-index="-1" data-ckey="searchTabArtRightFont">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>
4
-14>="" class="search_tab active">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4
-14>="" class="Jso-S-Title" data-top="layerCB84
-14
-14> style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4
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-14>>4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4
-14>="" class="Jso-S-Title">4
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-14>="" class="Jso-S-Title" data-top="layerCB84
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-24 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>631F3D098DC3E3F3859862ECB31B" data-expr="attr.options.searchTabPrdLeft" data-index="-1" data-ckey="searchTabPrdLeftFont">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>631F3D098DC3E3F3859862ECB31B" data-expr="attr.options.searchTabPrdRight" data-index="-1" data-ckey="searchTabPrdRightFont">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>
4
-14>="" class="search_tab">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4
-14>="" class="Jso-S-Title" data-top="layerCB84
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-14>="" class="Jso-S-Title">4
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4
-14>="">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_product_list">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;">
4
-14>="" class="search_porduct_item" style="border-bottom-width: 1px; border-bottom-style: dashed; border-bottom-color: rgb(213, 213, 2134
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4
-14>="" class="oem_flex">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h![]()
4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>6c37d7ab7d02ab974 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>d690a.png"> 4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_item_img">4
-14>="" src="/public/vplugin/navbar1/assets/62e8570994
-14
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-14>="" class="searchimage_uploading iconfont icon-a-zu3182" style="display: none;">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_item_l">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
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4
-14>="" class="search_item_time">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_item_r" style="color: rgb(0, 0, 04
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4
-14>="" class="search_porduct_item" style="border-bottom-width: 1px; border-bottom-style: dashed; border-bottom-color: rgb(213, 213, 2134
-24 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="oem_flex">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h![]()
4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>6c37d7ab7d02ab974 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>d690a.png"> 4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_item_img">4
-14>="" src="/public/vplugin/navbar1/assets/62e8570994
-14
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4
-14>="" class="search_item_l">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
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4
-14>="" class="search_item_time">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_item_r" style="color: rgb(0, 0, 04
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4
-14>="" class="search_porduct_item" style="border-bottom-width: 1px; border-bottom-style: dashed; border-bottom-color: rgb(213, 213, 2134
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4
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4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>6c37d7ab7d02ab974 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>d690a.png"> 4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
4
-14>="" class="search_item_img">4
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-14
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4
-14>="" class="search_item_l">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
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4
-14>="" class="search_item_time">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h 4>;">4 style="font-size: inherit;font-weight: inherit;line-height: inherit;margin: 0;">h
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-14>="" class="search_item_r" style="color: rgb(0, 0, 04
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4
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4
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4
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4
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4
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4
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4
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精准医疗
◆ DoTa/DoTr检测技术在国内发展历程
| 2007 | 厦门恩成集团成立 | 2019 | DoTa/DoTr检测技术正式进入中国 |
| 2015 | 上海恩成医疗科技有限公司成立 | 2019 | Califano院士担任恩成首席科学顾问来华访问 |
| 2017 | 詹启敏院士工作站成立 | 2019 | 共同建立厦门生物医药港医学检验实验室 |
| 2018 | 与美国达尔文健康有限公司战略合作 | 2020 | 与各大医院建立临床课题研究 |
◆ DoTa/DoTr检测技术介绍
一、检测原理
对肿瘤组织进行全转录组（RNA-seq）的高通量测序+VIPER专利分析，精准捕获（定量）异常活性的癌蛋白及主调控蛋白（肿瘤检查点），按药物的有效性精准匹配靶向它们的药物。使肿瘤检查点“塌陷”，从而实现以癌蛋白为靶点的更精准的靶向
二、与基因检测区别
绝大多数靶向药物和化疗药物的作用点是蛋白质，所以DoTa/DoTr检测能有效避免仅根据基因状况去“猜想”下游RNA和蛋白质的盲目性，使病人从真正的
精准医疗
中获益，有效的避免病人“盲目试药”。
◆ 基因检测技术介绍
一、基因检测癌变靶向治疗的作用机制
对常见的34种实体肿瘤，根据权威药物和基因组数据库、文献等，挖掘最具代表性的靶向药物基因、化疗药物敏感或毒副作用基因、免疫检查点、MSI相关标记及MMR相关基因等，设计出多种基因组合，最大程度的为肿瘤的靶向治疗、化疗、免疫治疗提供基于基因层面的精准治疗方案。
二、基因检测覆盖的癌种
| 1 | 涎腺癌、口腔肿瘤、口咽癌、喉癌、下咽癌、鼻咽癌、甲状腺癌、鼻腔及鼻窦肿瘤 | 5 | 前列腺癌、肾癌、膀胱癌 |
| 2 | 肺癌、肝癌、恶性胞膜间皮瘤、纵膈肿瘤 | 6 | 神经上皮性肿瘤、垂体腺瘤 |
| 3 | 食管癌、胃癌、结直肠癌、胃肠间质瘤、胰腺癌、胆囊癌、肝外胆管癌 | 7 | 骨肿瘤、软组织瘤 |
| 4 | 宫颈癌、子宫内膜癌、子宫肉瘤、卵巢癌、乳腺癌 | 8 | 基层细胞癌、鳞状细胞癌、黑色素瘤 |
◆ 药企合作：
国外：哥伦比亚大学医学中心、凯特琳癌症中心、安德森癌症中心、西奈山医院等。
国内：北大肿瘤医院、中山大学附属肿瘤医院、厦门大学附属第一医院、浙江大学医学院附属第二医院等。
 |
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| 丹娜法伯癌症研究所 | 浙江大学医学院附属第二医院 |
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| 北京大学肿瘤医院 | 中山大学附属肿瘤医院 | 青岛大学附属医院 |
 哥伦比亚大学医学中心 |
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| 安德森癌症中心 | 凯特琳癌症中心 | |
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| 厦门大学附属第一医院 | 西奈山医院 |
